Digestion, inflammation, and the microbiome influence your health.

The link of blood glucose regulation, gastric acid, & microbiome 

Blood Sugar dysregulation can affect weight, cause headaches, tiredness, cravings, and waking up at night. Blood glucose levels are influenced by the kind of food, timing of food, activity level, chronic stress, dehydration, limited sleep, and toxic exposure. Gerard, C. & Vidal H. (2019) mentioned the link of obesity, diabetes, and an imbalance in the microbiome. The gut microbiome's makeup and function are players in glucose regulation an insulin sensitivity (Gerard, C. & Vidal, H., 2019).

Too little gastric acid can affect the breakdown of food or the ability to kill harmful bacteria.  A lot of the times, we confuse heartburn, reflux, and GERD to be caused by too much acid in the stomach.  An esophageal valve that is not functioning well and stomach content that have been sitting there for a long period of time can cause partially digested food to get through the esophagus.

  Hypochlorhydria (decreased stomach acid) are influenced by age, stress level, drinking, and smoking.  Filardo S, et al. (2022) research study concluded that low gastric acid leads to microbiome imbalance in the small intestine causing gastrointestinal problems (Filardo S, et al., 2022).

Microbiome impacts health and the development of diseases. (Ogunrionola, GA, et al. (2020) review on factors influencing the microbiome such as age, nutrition, lifestyle, chronic conditions, genetic predisposition, and hormones. Gut microbiome changes are seen in cancer, inflammatory conditions, cardiovascular disease, allergies, and infections.  Prebiotics and Probiotics can be tools for balancing the microbiome (Ogunrinola, GA, et al., 2020).

References:

Gérard C, Vidal H. Impact of Gut Microbiota on Host Glycemic Control. Front Endocrinol (Lausanne). 2019 Jan 30;10:29. doi: 10.3389/fendo.2019.00029. PMID: 30761090; PMCID: PMC6363653.

Filardo S, Scalese G, Virili C, Pontone S, Di Pietro M, Covelli A, Bedetti G, Marinelli P, Bruno G, Stramazzo I, Centanni M, Sessa R, Severi C. The Potential Role of Hypochlorhydria in the Development of Duodenal Dysbiosis: A Preliminary Report. Front Cell Infect Microbiol. 2022 Apr 19;12:854904. doi: 10.3389/fcimb.2022.854904. PMID: 35521214; PMCID: PMC9062108.   

Ogunrinola GA, Oyewale JO, Oshamika OO, Olasehinde GI. The Human Microbiome and Its Impacts on Health. Int J Microbiol. 2020 Jun 12;2020:8045646. doi: 10.1155/2020/8045646. PMID: 32612660; PMCID: PMC7306068.

 



 


 

 

 

 

 

 

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